Advancing Immunology and Infection Biology
Decoding host immune responses in infection, ageing, and immune-related disorders to improve patient outcomes.
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Call Us: +356 23403869
brendon.scicluna@um.edu.mt
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Our Location
Faculty of Health Sciences, and
Centre for Molecular Medicine & Biobanking
University of Malta
Malta

Contribute To Our Research

Innovative Research in Immunology
Bridging Science and Clinical Practice
We are a translational immunology and infection biology research lab focused on understanding how the human immune system shapes disease across infection, critical illness, and immune-mediated disorders. Our work bridges basic immunology and clinical medicine to generate insights with direct relevance to patient care.
A central pillar of our research is the identification of host immune archetypes in sepsis and severe infection, enabling the development of precision, host-directed therapies. In parallel, we investigate how ageing and immune dysregulation influence susceptibility to infection, immune recovery, and long-term outcomes.
Mapping Immune Systems, Translating Discovery into Care
Join us in our mission to transform basic discovery science into meaningful clinical impact. Our research leverages systems immunology approaches, integrating high-dimensional molecular, cellular, and clinical data to understand immune function as a dynamic and interconnected system.
Together, through collaborative and data-driven science, we aim to redefine how immune complexity is understood and harnessed to improve patient care across the lifespan.
Understanding Immunology and Infection Biology

Research on Ageing Processes and Immune Function
Research on the Immunopathology of Sepsis
Host Immune Archetypes and Precision Therapeutics
TIIL in the news & Publications
Our research labs specialize in translational immunology and infection biology, focusing on the intersection of basic science and clinical application. We aim to identify host immune archetypes of sepsis, guiding precision therapeutics for critical illness. Additionally, we investigate how ageing processes impact immune function, striving to enhance our understanding and treatment of these complex interactions.

Our Availability
We invite you to explore our research schedule. Our team is dedicated to advancing the field of immunology and infection biology, and we are here to assist you during our operating hours. Join us in our mission to bridge science and clinical application!
Monday
8:00 AM – 5:00 PM
Tuesday
8:00 AM – 5:00 PM
Wednesday
8:00 AM – 5:00 PM
Thursday
8:00 AM – 5:00 PM
Friday
8:00 AM – 5:00 PM
Saturday
8:00 AM – 12:00 PM
Sunday
Closed
